LymphedemaV1, Main, Exploration, bibRecord, 00CC87

Analysis of human sera for filarial IgM antibody using antigen fractions isolated from immune complexes.

Identifieur interne : 00CC87 ( Main/Exploration ); précédent : 00CC86; suivant : 00CC88

Analysis of human sera for filarial IgM antibody using antigen fractions isolated from immune complexes.

Auteurs : G B Prasad [Inde] ; B C Harinath

Source :

Journal of clinical laboratory analysis [ 0887-8013 ] ; 1993.

RBID : pubmed:8505701

Descripteurs français

KwdFr :
- Animaux, Anticorps antihelminthe (sang), Antigènes d'helminthe (immunologie), Complexe antigène-anticorps (immunologie), Filariose lymphatique (diagnostic), Humains, Immunoglobuline M (sang), Test ELISA, Wuchereria bancrofti (immunologie).
MESH :
- diagnostic : Filariose lymphatique.
- immunologie : Antigènes d'helminthe, Complexe antigène-anticorps, Wuchereria bancrofti.
- sang : Anticorps antihelminthe, Immunoglobuline M.
- Animaux, Humains, Test ELISA.

English descriptors

KwdEn :
- Animals, Antibodies, Helminth (blood), Antigen-Antibody Complex (immunology), Antigens, Helminth (immunology), Elephantiasis, Filarial (diagnosis), Enzyme-Linked Immunosorbent Assay, Humans, Immunoglobulin M (blood), Wuchereria bancrofti (immunology).
MESH :
- chemical , blood : Antibodies, Helminth, Immunoglobulin M.
- chemical , immunology : Antigen-Antibody Complex, Antigens, Helminth.
- diagnosis : Elephantiasis, Filarial.
- immunology : Wuchereria bancrofti.
- Animals, Enzyme-Linked Immunosorbent Assay, Humans.

Abstract

Filarial IgM antibody response to various antigenic fractions isolated from immune complexes by SDS-PAGE viz., IC-2, IC-4, IC-7, and IC-9, was studied by ELISA. The IgM antibody response to almost all antigenic fractions was seen more in microfilaraemic group compared to the clinical filariasis group. The antibody response to IC-9 antigen fraction as compared to other fractions was found significantly higher in microfilaraemic patients than in patients with clinical manifestations. Ninety percent of microfilariae carriers and 75% of clinical filarial patients have shown IgM isotype to IC-9 antigen. Studies with various lectins have revealed the Con A binding nature of IC-9 antigen. This study suggests that IC-9 antigen could be another candidate antigen in the immunodiagnosis of lymphatic filariasis.

PubMed: 8505701

Affiliations:

Inde

Le document en format XML

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<term>Antigens, Helminth (immunology)</term>
<term>Elephantiasis, Filarial (diagnosis)</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Humans</term>
<term>Immunoglobulin M (blood)</term>
<term>Wuchereria bancrofti (immunology)</term>
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<term>Complexe antigène-anticorps (immunologie)</term>
<term>Filariose lymphatique (diagnostic)</term>
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<term>Immunoglobuline M (sang)</term>
<term>Test ELISA</term>
<term>Wuchereria bancrofti (immunologie)</term>
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<term>Immunoglobulin M</term>
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<term>Antigens, Helminth</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Elephantiasis, Filarial</term>
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<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Filariose lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes d'helminthe</term>
<term>Complexe antigène-anticorps</term>
<term>Wuchereria bancrofti</term>
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<term>Enzyme-Linked Immunosorbent Assay</term>
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<front><div type="abstract" xml:lang="en">Filarial IgM antibody response to various antigenic fractions isolated from immune complexes by SDS-PAGE viz., IC-2, IC-4, IC-7, and IC-9, was studied by ELISA. The IgM antibody response to almost all antigenic fractions was seen more in microfilaraemic group compared to the clinical filariasis group. The antibody response to IC-9 antigen fraction as compared to other fractions was found significantly higher in microfilaraemic patients than in patients with clinical manifestations. Ninety percent of microfilariae carriers and 75% of clinical filarial patients have shown IgM isotype to IC-9 antigen. Studies with various lectins have revealed the Con A binding nature of IC-9 antigen. This study suggests that IC-9 antigen could be another candidate antigen in the immunodiagnosis of lymphatic filariasis.</div>
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Serveur d'exploration sur le lymphœdème

Analysis of human sera for filarial IgM antibody using antigen fractions isolated from immune complexes.

Analysis of human sera for filarial IgM antibody using antigen fractions isolated from immune complexes.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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